{"id":13646,"date":"2026-08-18T09:08:58","date_gmt":"2026-08-18T09:08:58","guid":{"rendered":"https:\/\/koshalsambada.in\/?p=13646"},"modified":"2026-08-18T09:08:58","modified_gmt":"2026-08-18T09:08:58","slug":"openais-former-top-exec-fidji-simo-admits-that-she-disagrees-with-dario-amodei-on-most-things-but-says-he-is-spot-on-treatment-of","status":"publish","type":"post","link":"https:\/\/koshalsambada.in\/?p=13646","title":{"rendered":"OpenAI&#8217;s former top exec Fidji Simo admits that she disagrees with Dario Amodei on most things, but says he is spot on treatment of &#8230;"},"content":{"rendered":"<p><br \/>\n<\/p>\n<div>\n<div class=\"e9jwa\">\n<div class=\"vdo_embedd\">\n<div class=\"GfdvZ\">\n<section class=\"_bIDB  clearfix id-r-component leadmedia undefined undefined  E9tg9 \" style=\"top:0px\">\n<div class=\"_bIDB\" data-ua-type=\"1\" onclick=\"stpPgtnAndPrvntDefault(event)\">\n<div class=\"ypVvZ\">\n<div class=\"WGttI\"><img src=\"https:\/\/static.toiimg.com\/thumb\/msid-133316392,imgsize-1040606,width-400,height-225,resizemode-4\/fidji-simo.jpg\" alt=\"OpenAI's former top exec Fidji Simo admits that she disagrees with Dario Amodei on most things, but says he is spot on treatment of ...\" decoding=\"async\" fetchpriority=\"high\"\/><\/div>\n<\/div>\n<\/div>\n<\/section>\n<\/div><\/div>\n<\/div>\n<p>Fidji Simo, former OpenAI executive and cofounder of biomedical startup ChronicleBio, said she disagrees with Anthropic CEO Dario Amodei on most issues but fully supports his stance that AI companies must deliver tangible medical breakthroughs.<!-- --> Responding to Amodei\u2019s weekend post, Simo wrote on X (formerly known as Twitter): \u201cI disagree with Dario on most things, but this is spot on\u2026 The thing that will work is actually curing cancer.\u201d<span class=\"id-r-component br\" data-pos=\"3\"\/><\/p>\n<p><h2>A rare point of agreement with Anthropic CEO Dario Amodei<\/h2>\n<\/p>\n<p>Simo&#8217;s comments came in an X post on Monday, made in direct response to Anthropic CEO Dario Amodei, who wrote over the weekend that AI companies need to deliver concrete breakthroughs if they want to win over an increasingly skeptical public. <!-- -->Quoting Amodei&#8217;s post, Simo wrote that she disagrees with him on most things, but found his point spot on: that claiming AI will cure cancer has become more of a clich\u00e9 than an inspiring statement, one most people now view as deceptive, and that what would actually work is curing cancer itself.<span class=\"id-r-component br\" data-pos=\"9\"\/>Amodei&#8217;s original remarks were part of a broader defense of Anthropic&#8217;s public messaging around AI. On Saturday, he had pushed back on the idea that he&#8217;s been excessively pessimistic about the technology&#8217;s potential, arguing instead that the AI industry has fueled public skepticism by making sweeping promises it hasn&#8217;t delivered on.<span class=\"id-r-component br\" data-pos=\"12\"\/><\/p>\n<p><h2>Amodei\u2019s criticism of AI industry<\/h2>\n<\/p>\n<p>Amodei had argued that sweeping promises \u2014 such as AI curing cancer \u2014 have become clich\u00e9s and risk fueling public skepticism. He said the industry must prove its value through concrete results rather than marketing. Simo echoed this, noting that while she believes AI can eventually cure all diseases, smarter models alone are not enough.<span class=\"id-r-component br\" data-pos=\"15\"\/><\/p>\n<p><h2>The bottleneck: Biological data<\/h2>\n<\/p>\n<p>Simo stressed that the \u201cbigger bottleneck\u201d lies in building the right biological datasets. <!-- -->\u201cAI can\u2019t reason its way to cures without the data needed to understand a particular disease,\u201d she wrote. She added that cancer research is best positioned for AI breakthroughs because decades of investment have produced extraordinary datasets across genomics, pathology, imaging, and clinical outcomes.<span class=\"id-r-component br\" data-pos=\"20\"\/><\/p>\n<p><h2>ChronicleBio\u2019s mission<\/h2>\n<\/p>\n<p>Simo cofounded ChronicleBio in 2025 to address gaps in data infrastructure for complex chronic diseases, which lack the robust datasets available in oncology. <!-- -->Her work reflects both professional and personal experience, as she has spoken about living with postural orthostatic tachycardia syndrome (POTS), a chronic condition that is difficult to diagnose and treat.<span class=\"id-r-component br\" data-pos=\"25\"\/><\/p>\n<p><h2>Read Fidji Simo\u2019s complete post here<\/h2>\n<\/p>\n<p><span class=\"em\" data-ua-type=\"1\" onclick=\"stpPgtnAndPrvntDefault(event)\">I disagree with Dario on most things, but this is spot on: \u201cAt this point, saying that AI will cure cancer is more a clich\u00e9 than it is inspiring, and most people think it is deceptive. The thing that will work is actually curing cancer.\u201d<\/span><span class=\"id-r-component br\" data-pos=\"29\"\/><span class=\"em\" data-ua-type=\"1\" onclick=\"stpPgtnAndPrvntDefault(event)\">The thing that frustrates me is that some people often draw a straight line from smarter models \u2192 cures, without acknowledging how much infrastructure is missing in between. We\u2019ve still got a lot of work to do, people. <\/span><span class=\"id-r-component br\" data-pos=\"31\"\/><span class=\"em\" data-ua-type=\"1\" onclick=\"stpPgtnAndPrvntDefault(event)\">The regulatory bottleneck gets a lot of attention. But the bigger bottleneck may be that in many places, we\u2019re lacking the right biological data. AI can\u2019t reason its way to cures if we haven\u2019t generated the data required to understand the disease in the first place.<\/span><span class=\"id-r-component br\" data-pos=\"35\"\/><span class=\"em\" data-ua-type=\"1\" onclick=\"stpPgtnAndPrvntDefault(event)\">Ironically, that\u2019s why I\u2019m most bullish on AI making dramatic progress in cancer first: decades of investment have produced extraordinary datasets across genomics, pathology, imaging, clinical outcomes, and more.<\/span><span class=\"id-r-component br\" data-pos=\"37\"\/><span class=\"em\" data-ua-type=\"1\" onclick=\"stpPgtnAndPrvntDefault(event)\">For complex chronic diseases, much of that infrastructure simply doesn\u2019t exist yet. The good news is that many companies (including  <\/span><a href=\"https:\/\/x.com\/ChronicleBioAI\" rel=\"noopener nofollow noreferrer\" styleobj=\"[object Object]\" class=\"\" target=\"\" commonstate=\"[object Object]\" frmappuse=\"1\">@ChronicleBioAI<\/a><span class=\"em\" data-ua-type=\"1\" onclick=\"stpPgtnAndPrvntDefault(event)\">) are racing to build it.<\/span><span class=\"id-r-component br\" data-pos=\"41\"\/><span class=\"em\" data-ua-type=\"1\" onclick=\"stpPgtnAndPrvntDefault(event)\">But model intelligence and biological infrastructure are going to have to scale together. I really do believe AI can cure all diseases but only if we build the infrastructure to translate intelligence into cures at the same pace that models improve (which is a high bar!). Otherwise, we risk having superintelligent AI with an incomplete picture of human biology, and delay that promise by years.<\/span><\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/timesofindia.indiatimes.com\/technology\/tech-news\/openais-former-top-exec-fidji-simo-admits-that-she-disagrees-with-dario-amodei-on-most-things-but-says-he-is-spot-on-treatment-of-\/articleshow\/133316342.cms\" target=\"_blank\" rel=\"noopener\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Fidji Simo, former OpenAI executive and cofounder of biomedical startup ChronicleBio, said she disagrees with Anthropic CEO Dario Amodei on most issues but fully supports his stance that AI companies must deliver tangible medical breakthroughs. Responding to Amodei\u2019s weekend post, Simo wrote on X (formerly known as Twitter): \u201cI disagree with Dario on most things, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":13647,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[31],"tags":[],"class_list":["post-13646","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-31"],"magazineBlocksPostFeaturedMedia":{"thumbnail":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","medium":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","medium_large":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","large":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","1536x1536":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","2048x2048":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","blogsy-small":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","blogsy-small-tall":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","blogsy-small-square":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","blogsy-small-masonry":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","blogsy-medium":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","blogsy-medium-masonry":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","blogsy-large":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg","blogsy-wide":"https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg"},"magazineBlocksPostAuthor":{"name":"admin","avatar":"https:\/\/secure.gravatar.com\/avatar\/8709732a479614e7a8aa24d3eb1b239f30dc6d90c61464ed495001e7a469d856?s=96&d=mm&r=g"},"magazineBlocksPostCommentsNumber":"0","magazineBlocksPostExcerpt":"Fidji Simo, former OpenAI executive and cofounder of biomedical startup ChronicleBio, said she disagrees with Anthropic CEO Dario Amodei on most issues but fully supports his stance that AI companies must deliver tangible medical breakthroughs. Responding to Amodei\u2019s weekend post, Simo wrote on X (formerly known as Twitter): \u201cI disagree with Dario on most things, [&hellip;]","magazineBlocksPostCategories":["\u0b26\u0b47\u0b36 \u0b2c\u0b3f\u0b26\u0b47\u0b36"],"magazineBlocksPostViewCount":1,"magazineBlocksPostReadTime":4,"magazine_blocks_featured_image_url":{"full":["https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg",400,225,false],"medium":["https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg",300,169,false],"thumbnail":["https:\/\/koshalsambada.in\/wp-content\/uploads\/2026\/08\/fidji-simo.jpg",150,84,false]},"magazine_blocks_author":{"display_name":"admin","author_link":"https:\/\/koshalsambada.in\/author\/admin"},"magazine_blocks_comment":0,"magazine_blocks_author_image":"https:\/\/secure.gravatar.com\/avatar\/8709732a479614e7a8aa24d3eb1b239f30dc6d90c61464ed495001e7a469d856?s=96&d=mm&r=g","magazine_blocks_category":"<a href=\"#\" class=\"category-link category-link-31\">\u0b26\u0b47\u0b36 \u0b2c\u0b3f\u0b26\u0b47\u0b36<\/a>","_links":{"self":[{"href":"https:\/\/koshalsambada.in\/index.php?rest_route=\/wp\/v2\/posts\/13646","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/koshalsambada.in\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/koshalsambada.in\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/koshalsambada.in\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/koshalsambada.in\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=13646"}],"version-history":[{"count":0,"href":"https:\/\/koshalsambada.in\/index.php?rest_route=\/wp\/v2\/posts\/13646\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/koshalsambada.in\/index.php?rest_route=\/wp\/v2\/media\/13647"}],"wp:attachment":[{"href":"https:\/\/koshalsambada.in\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=13646"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/koshalsambada.in\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=13646"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/koshalsambada.in\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=13646"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}